vCenter Advance settings is used to modify the vpxd.cfg configuration file. To view the configuration options available with Advance settings, login to Web Client and select vCenter server from vCenter Inventory list and navigate to Manage > Settings > Advanced Settings as sown below.

You can use Advanced Settings to add/edit entries to the vpxd.cfg file, but can’t delete them. A user should have Global.Settings privileges to make any configuration change from here. 

For e.g to see list of available options for certificate related settings, type certmgmt in search box and hit enter.

Some of the commonly used advanced settings are listed in below table:

For more information on vCenter Advance Settings, please see below articles

Advanced settings for vSphere 5.5 & 6.0

vpxd.cfg advance configuration

vCenter Certificate Management Default Values

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